出生年月

1983.6

职称

副教授

邮箱

Zhaoye@njtech.edu.cn

研究方向

药理学

个人简介

药学院硕士生导师，2011年毕业于北京协和医学院，后赴新加坡国立大学生命科学院从事博士后研究。曾主持国家自然科学基金项目青年基金项目与江苏省先进生物制造协同创新中心自由探索项目。目前主要研究方向为肝纤维化生物标志物及肝纤维化/早期肝硬化的分子机制探索；（2）HBV/HCV相关的转基因斑马鱼肝脏病理模型、发病机制研究及肝病治疗药物筛选；（3）基于微生态探索菌群在疾病发生中的免疫调控机制。

代表性的科研项目/著作/论文

Zhao Y*, L Nikita, Tzeng CM, Talin-1   interaction network in cellular mechanotransduction, International Journalof   Molecular Medicine,2022

Zhao Y, Lu C, Wang H, et.al, Identification   of hsa-miR-1275 as a novel biomarker targeting MECP2 for human epilepsy of   unknown etiology,Molecular Therapy-Methods & Clinical Development, 2020

Zhao Y*, Meng F, Ding C, et.al,   Gender-differentiated metabolic abnormalities of adult zebrafish with zinc   pyrithione (ZPT) -induced hepatotoxicity, Chemosphere, May, 2020

ZhaoY*, Wang H, Li T, et.al, Baicalin   ameliorates dexamethasone-induced osteoporosis by regulation of the   RANK/RANKL/OPG signaling pathway. Drug design, development and therapy, Jan,   2020

Zhao Y, Cai L, Wang H, et.al,   1,25-Dihydroxyvitamin D3 affects gastric cancer progression by repressing   BMP3 promoter methylation. OncoTargets and Therapy, 12:2343-2353, Mar, 2019

Zhao Y*,Liu Y, Sun   J, et.al, Acute toxic responses of embryo-larval zebrafish to zinc pyrithione   (ZPT) reveal embryological and developmental toxicity, Chemosphere,   205:62-70, Aug, 2018.

Zhao Y, Huang X, Ding TW, Gong Z,   Enhanced angiogenesis, hypoxia and neutrophil recruitment during Myc-induced   liver tumorigenesis in zebrafish, Scientific Reports, 6:31952 Aug, 2016